Table 2.
Univariate Cox (uni-cox ) and multivariate Cox (multi-cox ) regression analysis of OS in TCGA-EC (n=528).
| Clinicopathological characteristics | Uni-cox | Multi-cox | ||
|---|---|---|---|---|
| HR (95%CI) | P value | HR (95%CI) | P value | |
| POLE mutation status (Mutation vs wild) | 0.299 (0.131-0.686) | 0.004 | 0.296 (0.126-0.693) | 0.005 |
| Age | 1.038 (1.016-1.060) | <0.001 | 1.020 (0.998-1.043) | 0.082 |
| Histological subtypes (Endometrioid vs others) | 2.766 (1.181-6.482) | 0.019 | 1.502 (0.626-3.601) | 0.36 |
| FIGO stage (III+IV vs I+II) |
3.746 (2.451-5.725) | < 0.001 | 4.332 (2.806-6.689) | < 0.001 |