Table 3.
Correlations between miR-451a expression with clinical features in 40 ATC patients
| Variables | Cases | miR-451a | χ2 value | P value | |
|---|---|---|---|---|---|
| Low (n = 20) | High (n = 20) | ||||
| Sex | 1.905 | 0.166 | |||
| Men | 28 | 12 | 16 | ||
| Women | 12 | 8 | 4 | ||
| Ages | 0.1023 | 0.7491 | |||
| < 60 | 17 | 9 | 8 | ||
| ≥ 60 | 23 | 11 | 12 | ||
| Primary tumor size | 0.4396 | 0.5073 | |||
| < 6 cm | 14 | 8 | 6 | ||
| ≥ 6 cm | 26 | 12 | 14 | ||
| Lymph node metastasis | 0.6455 | 0.5186 | |||
| N0 | 16 | 9 | 7 | ||
| N1 | 24 | 11 | 13 | ||
| Distant metastasis | 0.4762 | 0.4902 | |||
| M0 | 28 | 13 | 15 | ||
| M1 | 12 | 7 | 5 | ||
| Stage (AJCC, 2010) | 2.340 | 0.3104 | |||
| IVA | 14 | 9 | 5 | ||
| IVB | 12 | 6 | 7 | ||
| IVC | 14 | 5 | 9 | ||
The median value of miR-451a expression was used as the cutoff for dividing patients into a high-expression group (n = 20) and a low-expression group (n = 20). P value when expression levels were compared using the Pearson Chi-square test