Table 2.
Primary and secondary outcomes according to HOMA-IR groups
| HOMA-IR groups | ||||||
|---|---|---|---|---|---|---|
| Low (n = 1454) | Moderate (n = 1414) | High (n = 1446) | p-value | p’ | p” | |
| New onset Diabetes | 43 (3.0) | 37 (2.6) | 84 (5.8) | < 0.001 | < 0.001 | < 0.001 |
| Chronic kidney disease | 123 (8.5) | 129 (9.3) | 173 (12.2) | 0.002 | 0.001 | 0.007 |
| Macrovascular events | 41 (2.9) | 26 (1.8) | 35 (2.4) | 0.156 | 0.407 | 0.263 |
| Coronary artery disease or MI | 29 (2.0) | 15 (1.5) | 20 (1.4) | 0.052 | 0.095 | 0.610 |
| Ischemic stroke | 12 (0.8) | 11 (0.8) | 15 (1.0) | 0.809 | 0.707 | 0.511 |
Values are presented as number (%), p-values were calculated using Kaplan–Meier survival analysis with the log rank test. P′ is for the comparison between the low and high HOMA-IR groups. p” is for the comparison between the moderate and high HOMA-IR groups