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. 2023 Nov 2;14:1280299. doi: 10.3389/fimmu.2023.1280299

Table 2.

Global population coverage of the PP13138R vaccine for HLA I and II alleles.

Population/area Class I Class II
Coverage a Average_hit b Pc90 c Coverage a Average_hit b Pc90 c
Central Africa 31.89% 0.82 0.15 75.00% 1.62 0.4
Central America 1.40% 0.01 0.1 98.31% 5.36 3.48
East Africa 40.83% 1.15 0.17 83.43% 2.16 0.6
East Asia 73.63% 2.38 0.38 67.03% 2.55 0.3
Europe 65.15% 2.14 0.29 69.48% 2.29 0.33
North Africa 46.50% 1.12 0.19 73.52% 2.37 0.38
North America 69.39% 2.32 0.33 86.44% 3.7 0.74
Northeast Asia 81.17% 2.39 0.53 90.13% 3.72 1.01
Oceania 66.73% 1.82 0.3 93.51% 3.83 1.2
South America 45.62% 1.51 0.18 90.26% 4.42 1.05
South Asia 52.68% 0.91 0.21 66.30% 2.23 0.3
Southeast Asia 79.95% 2.56 0.5 81.79% 2.62 0.55
Southwest Asia 47.28% 1.11 0.19 68.41% 2.47 0.32
West Africa 49.18% 1.37 0.2 85.86% 2.32 0.71
West Indies 41.98% 1.09 0.17 72.44% 2.18 0.36
World 67.14% 2.15 0.3 73.08% 2.64 0.37
Average 52.42 1.49 0.25 79.69 2.9 0.76
a

projected population coverage.

b

average number of epitope hits/HLA combinations recognized by the population.

c

minimum number of epitope hits/HLA combinations recognized by 90% of the population.