ATB	active tuberculosis
BCG	bacillus Calmette-Guérin
CTL	cytotoxic T lymphocytes
ELISPOT	enzyme-linked immunospot assay
GRAVY	grand average of hydropathicity
HTL	helper T lymphocytes
HCs	healthy controls
IL-2	interleukin-2
IFN-γ	interferon gamma
IEDB	immune epitope database
LTBI	latent tuberculosis infection
MTB	Mycobacterium tuberculosis
NHFPC	National Health and Family Planning Commission of China
PBMCs	peripheral blood mononuclear cells
SEM	standard error of the mean
TLR	toll-like receptor
TB	tuberculosis
TNF-α	tumor necrosis factor
WHO	World Health Organization
MEV	Multi-epitope vaccine
PTB	pulmonary tuberculosis
LMICs	low- and middle-income countries
HLA-I	human leukocyte antigen I
IGRA	interferon-gamma release test
ESAT-6	EC test, recombinant MTB fusion protein of early secretory antigenic target protein 6-kDa
CFP-10	culture filtrate protein 10 kDa
HIV	human immunodeficiency virus
MHC II	major histocompatibility complex II
PDB	protein data bank
MMDB	Molecular Modeling Database
E. coli	Escherichia coli
LB	Luria-Bertani
SDS-PAGE	sodium dodecyl sulfate-polyacrylamide gel electrophoresis
IFN-γ+	interferon-gamma positive
PBS	phosphate-buffered saline
TNF-α	tumor necrosis factor-α
CBA	Cytometric Bead Assay
SFCs	spot-forming cells
PCA	principal component analysis
DCs	dendritic cells
Th	helper T
ANOVA	one-way analysis of variance.