Fig 6.

Female CBA/J mice were transurethrally inoculated with a 1:1 mixture of HI4320 (wt) and the indicated mutant. After 7 days, bacteria were quantitatively cultured and competitive indices were calculated. Each symbol represents an individual mouse. Bars indicate median values and the dotted line at y = 0 represents no competitive advantage for either wild type or mutant. P values were assessed using the Wilcoxon signed rank test (*P < 0.05; **P < 0.01; ns, not significant). ND, not determined; a competitive index could not be determined because no bacteria were recovered.