Table 1.
Cytoskeleton remodeling, regulation of actin cytoskeleton by the kinase effectors of Rho GTPases
| Gene symbol | Object type | Description | p-value |
|---|---|---|---|
| Arhgdia | Regulators (GDI, GAP, GEF) | Rho GDP-dissociation inhibitor 1 | 0.004 |
| Cdc42bpb | Protein kinase | Serine/threonine-protein kinase MRCK beta | 0.006 |
| Arpc1b | Generic binding protein | Actin-related protein 2/3 complex subunit 1B | 0.008 |
| Pkn1 | Protein kinase | Serine/threonine-protein kinase N1 | 0.009 |
| Dstn | Generic binding protein | Destrin, actin depolymerizing protein | 0.014 |
| Cfl1 | Generic binding protein | Cofilin-1 | 0.014 |
| Add1 | Generic binding protein | Alpha-adducin | 0.035 |
| Myl6 | Generic binding protein | Myosin, light polypeptide 6 | 0.036 |
| Msn | Generic binding protein | Moesin | 0.039 |
| Myh10 | Generic binding protein | Myosin, heavy polypeptide 10 | 0.041 |
| Rhoa | RAS - superfamily | Transforming protein RhoA | 0.042 |
| Mylk | Protein kinase | Myosin, light polypeptide kinase | 0.045 |
| Myl12b | Generic binding protein | Myosin regulatory light chain 12b | 0.047 |
| Actn4 | Generic binding protein | Alpha-actinin 4, F-actin cross-linking protein | 0.053 |
| Cdc42 | RAS - superfamily | Cell division control protein 42 homolog | 0.053 |
| Vcl | Generic binding protein | Vinculin, F-actin binding protein | 0.055 |