Table 2. In Vitro Antiproliferative Effects (IC₅₀, μM) of Compounds 7a–q against Panc-1, PC3, MDA-MB-231, and HDF Cell Lines^a.

compounds	R	Panc-1	PC3	MBA-MB-231	HDF
7a	H	92.48 ± 0.05	91.25 ± 0.077	87.31 ± 0.063	>100
7b	3-OH	73.48 + 0.055	84.44 + 0.062	84.61 + 0.067	>100
7c	2-Me	60.63 ± 0.051	65.34 ± 0.052	66.17 ± 0.043	>100
7d	3-Me	65 ± 0.047	72.35 ± 0.063	65.94 ± 0.051	>100
7e	4-Me	48.10 ± 0.018	53.19 ± 0.024	65.47 ± 0.041	>100
7f	3-OMe	69.12 ± 0.039	78.98 ± 0.058	64.47 ± 0.05	>100
7g	4-OMe	60 ± 0.047	68.28 ± 0.039	61.01 ± 0.029	>100
7h	4-F	66.4 ± 0.046	74.6 ± 0.051	70.62 ± 0.054	>100
7i	3-Cl	21.4 + 0.016	30.01 ± 0.02	17.9 ± 0.014	>100
7j	4-Cl	46.95 ± 0.021	57.91 ± 0.04	53.34 ± 0.037	>100
7k	3-Br	58.19 ± 0.022	66.29 ± 0.037	62.01 ± 0.041	>100
7l	4-Br	73.92 ± 0.043	60.04 ± 0.031	58.03 ± 0.04	>100
7m	3-NO2	12.54 ± 0.001	17.66 ± 0.012	13.14 ± 0.005	>100
7n	4-NO2	46.35 + 0.028	60.17 + 0.045	61.66 + 0.052	>100
7o	3-OMe-4-OH	14.95 + 0.001	17.76 + 0.014	15.09 + 0.001	>100
7p	2,4-Cl2	72.48 ± 0.058	76.3 ± 0.046	81.84 ± 0.063	>100
7q	3,4,5-(OMe)3	72.81 ± 0.052	81.28 ± 0.06	67.4 ± 0.048	>100
etoposide		24.35 ± 0.001	32.15 ± 0.021	30.63 ± 0.014	>100

^aValues are the means of three replicates ± standard deviation (SD).