rmbTBI does not result in impaired glia-enriched mitochondrial respiration from various brain regions. Seahorse XFe96 was utilized to measure distinct states of mitochondrial respiration in glia-enriched mitochondria at 2 days following rmbTBI and subsequent MP201 treatment. (A) State III, State IV, State VCI, and State VCII respiration in glia-enriched mitochondria from the AEP region (n = 7–8/group). (B) State III, State IV, State VCI, and State VCII respiration in glia-enriched mitochondria from the PFC (n = 7 − 8/group). (C) State III, State IV, State VCI, and State VCII respiration in glia-enriched mitochondria from the hippocampus (n = 7–8/group). Data represented as mean ± SEM; p ≤ 0.05*, p ≤ 0.01** by one-way ANOVA with Dunnett's post hoc compared with rmbTBI Vehicle (B). AEP, amygdala/entorhinal/piriform cortex; ANOVA, analysis of variance; OCR, oxygen consumption rate; PFC, prefrontal cortex; rmbTBI, repeated mild blast traumatic brain injury; SEM, standard error of the mean.