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. 2004 Mar;9(1):88–98. doi: 10.1379/CSC-9R.1

Fig 7.

Fig 7.

Lumbar-4 sensory neuron survival with Hsp70 or Hsc70 treatment (or both). These data were analyzed in the same manner as that for the motor neurons in Figure 6. The overall analysis of variance was significant (P = 0.0002), and comparison of the mean number of sensory neurons in the L4-DRG of the saline-treated group with that of the contralateral, uninjured group showed that there was a significant loss of sensory neurons caused by axotomy (P < 0.01, not indicated for the sake of clarity). This axotomy-induced neuronal death was inhibited after treatment with only the higher doses of rhHsp (25–30 μg), with the 25-μg dose of rbHsc, or the 1:1 mix of rhHsp-rbHsp (*P < 0.05 compared with the saline-treated group)