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. 2023 Oct 26;19(21):7478–7495. doi: 10.1021/acs.jctc.3c00814

Table 1. Docking Power and Screening Power of RTMScore on CASF-2016 Data Set When Using the Unbiased Pocket Selection Method, Compared with Other State-of-the-Art Models.

  Docking Power (Success Rate)
Forward Screening Power
 
Model Name Without native poses With native poses EF1% Top1 success rate Reference
RTMScore1-unBiased 0.877 0.909 24.84 0.509 This work
RTMScore1-Biased 0.937 0.986 28.78 0.737 (171)
DeepDock 0.870 16.41 0.439 (170)
PIGNet 0.870 19.6 0.554 (172)
DeepBSP 0.872 0.885 (173)
OnionNet-SFCT 0.937 15.50 0.421 (174)
ΔLin_F9XGB 0.867 12.61 0.404 (154)
ΔVinaXGB 0.916 13.14 0.368 (152)
ΔVinaRF20 0.849 0.891 11.73 0.421 (149)
KORP-PL 0.856 0.891 22.23 0.421 (175)
GlideScore-SP 0.846 0.877 11.44 0.368 (23)
ChemPLP@GOLD 0.832 0.860 11.91 0.351 (176)
AutoDock Vina 0.846 0.902 7.70 0.298 (22)