Table 3b. Echocardiograms in TMED-2 Dataset.

Hemodynamic values were extracted from the medical record. Screening tasks correspond to the automated diagnostic tasks studied: 1) Any AS (vs none), 2) Early AS vs Significant AS, 3) No significant AS (vs significant AS). Not all values are available for every study, the number reporting each value are shown in the left hand column. All values are median +/− interquartile range (IQR) unless otherwise specified. AS is aortic stenosis. LV is left ventricle, V2 max is the peak continuous wave velocity. AV is aortic valve. LV ejection fraction was assessed by integrating the biplane method of disks summation (modified Simpson’s rule) with overall visual assessment. Max gradient is the maximum continuous wave gradient across the aortic valve. Mean gradient is the mean continuous wave gradient across the aortic valve. mmHg is millimeters of mercury.

	Echocardiogram Study Characteristics
Screening Task	All	No AS	Early AS		Significant AS
AS Grade		No AS	Mild AS	Mild/moderate AS	Moderate AS	Severe AS
N	599	127 (21.2%)	144 (24.0%)	27 (4.5%)	132 (22.0%)	169 (28.2%)
Stroke Volume, mL (n = 566)	59.6 (46–75.6)	54 (41–70.8)	61 (47–83.1)	50 (43.0–69.7)	66.0 (52.0–83.0)	59.0 (47.8–72.0)
LV ejection fraction, % (n = 599)	60 (55–65)	55 (45–60)	60 (55–65)	60 (55–65)	60 (55–65)	60 (55–65)
V2 max, m/s (n = 507)	2.89 (2.29–3.65)	1.73 (1.28–2.00)	2.45 (2.32–2.64)	2.89 (2.80–2.97)	3.26 (3.11–3.47)	4.32 (3.96–4.65)
AV max gradient mmHg (n = 508)	34.4 (21–52.7)	12.1 (6.8–16.1)	24.1 (21.8–28.1)	34.1 (32.1–35.2)	42.6 (38.9–48.4)	74.4 (63.0–87.0)
AV mean gradient, mmHg (n = 491)	18.1 (11.9–30.0)	6.7 (4.1–8.5)	13.2 (11.6–15.1)	17.8 (15.8–19.4)	23.0 (20.2–26.2)	42.0 (35.0–50.0)