Table 3:
Postoperative intestinal and outcomes information in infants with and without cholestasis
| N | Total (N = 91) | No cholestasis (N = 29) | Cholestasis (N = 62) | p-value | |
|---|---|---|---|---|---|
|
| |||||
| Postoperative intestinal features | |||||
| Time to reach full feeds (days, mean ± SD) | 66 | 71.3 (45.6) | 58.1 (47.8) | 77.1 (44.0) | 0.12 |
| Days of starting feeds (days, mean ± SD) | 80 | 19.3 (17.0) | 14.0 (10.0) | 21.5 (18.8) | 0.08 |
| Days of TPN (days, mean ± SD) | 90 | 97.6 (56.1) | 74.7 (48.1) | 108.4 (56.6) | 0.007 |
| Postoperative ileus (days, mean ± SD) | 81 | 17.6 (15.5) | 13.4 (10.0) | 19.2 (17.0) | 0.13 |
| Surgical complication, n (%) | 91 | 39 (42.9) | 8 (27.6) | 31 (50.0) | 0.044 |
| Single complication, n (%) | 91 | 23 (25.3) | 6 (20.7) | 17 (27.4) | 0.49 |
| >1 complication, n (%) | 91 | 14 (15.4) | 1 (3.4) | 13 (21.0) | 0.031 |
| Wound dehiscence, n (%) | 91 | 15 (16.5) | 2 (6.9) | 13 (21.0) | 0.09 |
| Wound infection, n (%) | 91 | 8 (8.8) | 1 (3.4) | 7 (11.3) | 0.22 |
| Adhesions, n (%) | 91 | 20 (22.0) | 4 (13.8) | 16 (25.8) | 0.20 |
| Fistula, n (%) | 91 | 5 (5.5) | 0 (0.0) | 5 (8.1) | 0.12 |
| Intestinal failure, n (%) | 83 | 42 (50.6) | 6 (25.0) | 36 (61.0) | 0.003 |
| Outcomes | |||||
| Weight z-scores @36 weeks | 72 | −1.67 (−2.1, −0.88) | −1.68 (−2.04, −1.05) | −1.54 (−2.11, −0.87) | 0.38 |
| Length z-scores @36 weeks | 72 | −1.92 (−3.26, −1.30) | −1.67 (−3.66, −1.19) | −2.04 (−3.26, −1.35) | 0.30 |
| Weight-for-length z-scores @36 weeks | 72 | −1.11 (−1.74, −0.194) | −1.32 (−1.76, −0.76) | −1.0 (−1.73, −0.12) | 0.025 |
| Head circumference z-scores @36 weeks | 72 | −2.16 (−2.72, −0.98) | −1.92 (−2.82, −0.942) | −2.39 (−2.77, −0.92) | 0.30 |
| White-matter injury, n (%) | 60 | 28 (46.7) | 9 (50.0) | 19 (45.2) | 0.74 |
| Length of stay (days, mean ± SD) | 91 | 140.5 (81.6) | 112.4 (84.2) | 153.7 (77.5) | 0.024 |
| Death | 91 | 22 (24.2) | 6 (20.7) | 16 (25.8) | 0.60 |
The presence of bold values signified p < 0.05