TABLE 3.
Relationship between predictors of event-free survival in children with Alagille syndrome treated with maralixibat
| Variable 1 | Variable 2 | Pearson correlation coefficient | p |
|---|---|---|---|
| Total bilirubin levels at week 48 | sBA levels at week 48 | 0.72 | <0.0001 |
| Total bilirubin levels at week 48 | Change in pruritusa from baseline to week 48 | 0.35 | 0.0019 |
| sBA levels at week 48 | Change in pruritusa from baseline to week 48 | 0.39 | 0.0005 |
As assessed by ItchRO(Obs).
Abbreviations: ItchRO(Obs), Itch-Reported Outcome (Observer); sBA, serum bile acids.