Table 2.

Effect of IL-13 on chemokine concentrations (pg/ml) in arthritic joints in mice

Group	KC	MIP1α
ICA, day 3
AxCANI	56 ± 8	303 ± 6.8
AxCAhIL-13	196 ± 31*	344 ± 96
ICA, day 7
AxCANI	10 ± 6	157 ± 25
AxCAhIL-13	184 ± 26*	268 ± 98

Concentrations of KC and MIP1α were detected in synovial washouts of arthritic knee joints 3 and 7 days after arthritis induction. KC concentrations were significantly higher in arthritic knee joints injected with AxCAhIL-13 both at day 3 and 7. *P < 0.05 in comparison with AxCANI. AxCAhIL-13, adenovirus encoding interleukin-13; AxCANI, adenovirus encoding no gene; ICA, immune-complex-mediated arthritis; KC, mouse homologue for human IL-8; MIP 1α, macrophage inflammatory protein 1α.