Table 3. Comparison of mask-breathlessness score change from baseline in the aroma- and placebo-seal use groups.

Mask Breathlessness	Adjusted Means (95% CI)		1 week			2 week
	1 week	2 week	Differences of LSMD	p-value	Effect size	Differences of LSMD	p-value	Effect size
Aroma-seal use group (n = 31)	−0.72 (−0.94 to −0.49)	−0.62 (−0.87 to −0.37)	−0.49 (−0.81 to −0.17)	0.004	0.78	−0.53 (−0.88 to −0.18)	0.004	0.77
Placebo-seal use group (n = 30)	−0.23 (−0.46 to 0.004)	−0.09 (−0.34 to 0.16)

LSMD, least squares mean difference