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. 2023 Nov 16;18(11):e0294357. doi: 10.1371/journal.pone.0294357

Table 4. Comparison of WHO-5 score changes from baseline at the end of the two-week intervention in the aroma- and placebo-seal groups.

Adjusted Means (95% CI) Differences of LSMD p-value Effect size
Aroma-seal use group (n = 31) Placebo-seal use group (n = 30)
Total Score 3.32 (2.15 to 4.49) 1.67 (0.48 to 2.85) 1.66 (−0.01 to 3.33) 0.05 0.51
W1 0.42 (0.12 to 0.71) 0.20 (−0.10 to 0.50) 0.22 (−0.20 to 0.64) 0.3 0.27
W2 0.80 (0.56 to 1.05) 0.37 (0.12 to 0.62) 0.44 (0.09 to 0.79) 0.02 0.64
W3 0.60 (0.27 to 0.93) 0.28 (−0.06 to 0.62) 0.32 (−0.16 to 0.79) 0.19 0.34
W4 0.92 (0.52 to 1.32) 0.55 (0.15 to 0.95) 0.37 (−0.19 to 0.94) 0.19 0.34
W5 0.60 (0.28 to 0.92) 0.25 (−0.08 to 0.58) 0.35 (−0.11 to 0.81) 0.13 0.40

LSMD, least squares mean difference