TABLE 1.
Subject characteristics
| Control (n = 12) | α-trait (n = 15) | P | |
|---|---|---|---|
| Age, y | 28.7 [±13.4] | 40.3 [±16.3] | .060* |
| Sex | .795† | ||
| Male | 5 [42%] | 7 [47%] | |
| Female | 7 [58%] | 8 [53%] | |
| Race/ethnicity | .014‡ | ||
| Asian | 1 [8%] | 9 [60%] | |
| Black | 11 [92%] | 5 [33%] | |
| White | 1 [7%] | ||
| Vitals | |||
| Height, cm | 167 [±9.8] | 172 [±8.3] | .206§ |
| Weight, kg | 71.3 [±20] | 78.2 [±19] | .366§ |
| BMI, kg/m2 | 25.6 [±7.5] | 26.4 [±5.4] | .783§ |
| SBP, mm Hg | 118 [±13] | 128 [±11] | .195§∥ |
| DBP, mm Hg | 73 [±11] | 80 [±9] | .205§∥ |
| HR, bpm | 76.2 [±14] | 75.4 [±8.6] | .859§ |
| RR, bpm | 15.1 [±2.7] | 13.9 [±2.0] | .287* |
| O2 saturation, % | 98 [±1.2] | 98 [±0.8] | .203* |
| Laboratory values | |||
| Hemoglobin, g/dL | 13.1 [±1.4] | 12.7 [±1.4] | .511§ |
| MCV, fL | 85 [±7.3] | 76.6 [±8.4] | .010§ |
| Absolute reticulocyte, K/μL | 62.6 [±24.7] | 67.6 [±18.9] | .510* |
| LDH, U/L | 478 [±106] | 570 [±91] | .027§¶ |
| Plasma hemoglobin, mg/dL | 9.8 [±9.1] | 7.9 [±6.3] | .401§ |
Note: Values expressed as mean [±SD] for continuous variables, and as n [%] for categorical variables. The P value was determined by
Wilcoxon rank sum test,
Pearsonʼs χ2 test,
Fisherʼs exact test or
Student t test. Bold P values indicate significant differences (P < .05).
Corrected for age.
Both values are in the normal range.
Abbreviations: BMI, body mass index; DBP, diastolic blood pressure; HR, heart rate; LDH, lactate dehydrogenase; MCV, mean corpuscular volume; RR, respiratory rate; SBP, systolic blood pressure.