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. Author manuscript; available in PMC: 2023 Nov 16.
Published in final edited form as: Anal Chem. 2023 Jan 24;95(5):2732–2740. doi: 10.1021/acs.analchem.2c03719

Figure 5. FDR benefits of p-value correction in 3,000 simulations with both true and false H0i.

Figure 5.

A. Example of Model 3 simulation with both true and false underlying H0i. Parameters: m = 2,000, Nc = Nt = 11, Typical Biol. Var. (C.V.) = 0.05, Technical Var. (C.V.) = 0.03, Typical Effect = 1, k = 4, θ = 0.5, Significance Threshold = 0.05. B. FDP distributions and FDR estimates. FDR^=mean(FDP). C. For each integer FDP between 0% and 100%, the percent of simulations that yielded an FDP greater than that value (X) is plotted along the Y axis.