TABLE 1.

Summary of sequencing results ^a

Average total reads per sample	35055111.3 (5,661,278–145,431,302)
Average % of reads aligned	53.7% (1.4%–98.44%)
Average mean coverage	53.5x (0.25×–168.13×)
Average genome callable (% covered by ≥5 reads)	70.8% (1.4%–98.4%)
Average genome callable, for samples with parasitemia >0.2% (% covered by ≥5 reads)	88.9% (3.2%–98.4%)
Average genome callable, for samples with parasitemia at LOD, 0.2% (% covered by ≥5 reads)	50.1% (1.4%–96.6%)

^a Sequences were obtained from 120 patients. Greater than 70% of the genome was covered by ≥5 reads across samples. Coverage was correlated with parasitemia (Fig. S1), with only 50% of the genome covered by ≥5 reads for samples with a parasitemia at the limit of detection (LOD) (0.2% or 1 in 500 infected RBCs).