TABLE 3.
Regions of the genome with high levels of IBD sharing a
| Region of high IBD sharing | Gene ID | Description | Start | End |
|---|---|---|---|---|
| CHR 6 (PF3D7_6:1,094,803–1,263,547 | PF3D7_0629500 | Amino acid transporter 1 | 1,213,948 | 1,216,005 |
| CHR 8 (PF3D7_8:466,571–483,850) | PF3D7_0810800 | Hydroxymethyldihydropterin pyrophosphokinase-dihydropteroate synthase | 548,200 | 550,616 |
| CHR 12 (PF3D7_12:776,039–910,983) | PF3D7_1224000 | GTP cyclohydrolase 1 | 974,226 | 976,097 |
| PF3D7_122910 | Multidrug resistance-associated protein 2 | 1,192,888 | 1,199,214 | |
| CHR 13 (PF3D7_13:73,919–87,2914) | PF3D7_1317000 | U4/U6.U5 tri-snRNP-associated protein 2, putative | 708,346 | 710,268 |
| PF3D7_1317100 | DNA replication licensing factor MCM4 | 711,924 | 711,943 | |
| PF3D7_1317200 | AP2 domain transcription factor AP2-FG, putative | 721,961 | 729,979 | |
| CHR 14 (PF3D7_14:1,737,499–2,703,922) | PF3D7_1462500 | Conserved Plasmodium protein, unknown function | 2,544,824 | 2,549,785 |
| PF3D7_1462600 | Conserved Plasmodium membrane protein, unknown function | 2,550,692 | 2,552,432 |
a
Segments of the genome with a proportion of pairs IBD >0.0172 (approximately the peak of chromosome 8) are listed. Candidate genes in and around the regions of high IBD sharing are shown.