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. 2023 Oct 6;14(5):e00818-23. doi: 10.1128/mbio.00818-23

Fig 1.

Fig 1

The three chimeric DENV4/2 ED chimeric viruses have each surface-exposed ED of DENV4 replaced with DENV2 residues. (A) Organization of DENV genome and schema of changes of the chimeric panel. DENV2 regions are shown in pink, and DENV4 regions are in blue-green. C, capsid; prM, pre-membrane; M, membrane; ED, envelope domain; TM, transmembrane.