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. 2023 Sep 14;14(5):e01840-23. doi: 10.1128/mbio.01840-23

TABLE 1.

Differentially expressed genes (DEGs) associated with cell wall integrity in three Aspergillus species’ conidia versus hyphae

Cell wall-related gene cluster(# of genes in the cluster) Upregulated in conidia Downregulated in conidia
(A) In Aspergillus nidulans.
 Trehalose biogenesis (5) tpsA, tpsC, ccg9, orlA, tppC -
 Chitin biogenesis (17) chsA, chsB, chsC, chsD, chsF, chsG, csmB, csmA, chs5, chs7, AN1554, chs7-like, puma, ungA, gnaA, gfaA AN8765
 β-glucan biosynthesis (12) fksA, gelA, gelB, gelC, gelE, btgA, crhD, rhoA, gsaA, sunA btgD
 Melanin (9) wA, ayg1, arp2, abr2 arpA
 Pyomelanin (4) hmgX, hppD maiA
(B) In Aspergillus flavus.
 Trehalose biogenesis (5) tps1, AFLA_002830, ccg9, AFLA_131370
 Chitin biogenesis (17) chsA, chsE, chsF, chsG, AFLA_136040, chs3, chs5, chs7, AFLA_131730, chs7-like, AFLA_127350, AFLA_071350, AFLA_091260, AFLA_037960
 β-glucan biosynthesis (10) fksP, gel1, gel2, AFLA_121370, AFLA_129440, rho1, AFLA_048250, uth1 btg1, scw4
 DHN-melanin (6) pksP, AFLA_045660 arpA
 Pyomelanin (4) AFLA_036100, AFLA_036110, maiA bck1
(C) In Aspergillus fumigatus.
 Trehalose biogenesis (6) tpsA, tpsB
 Chitin biogenesis (17) chsA, chsB, chsC, chsD, chsF, chsG, csmB, Afu6g02510, chs3, chs7, Afu6g02940, Afu1g07110, agm1, Afu7g02180, gfa1
 β-glucan biosynthesis (13) fks1, gel1, gel2, gel3, gel4, gel5, gel7, bgt1, rho1, Afu5g05770
 DHN-melanin (6) encA, ayg1, arp2, abr1, abr2 Afu4g13390
 Pyomelanin (4) hmgX, hppD, maiA bck1