Table 1.
Demographics and colonoscopy findings of patients with positive MT-sDNA
| Unblinded | Blinded | p-value | |
|---|---|---|---|
|
Patients N |
172 | 72 | |
| Median age, years (interquartile range) | 69 (61, 75) | 70 (65, 75) | 0.37 |
| Male (%) | 38 | 46 | 0.32 |
| Colonoscopic Findings | |||
| Median number of polyps, n (IQR) | 2 (1, 4) | 1(0, 2) | 0.0007 |
| HP only, n (%) | 14 (8%) | 5 (7%) | 1.0 |
| Any SSA/P or adenomatous polyp, n (%) | 120 (70%) | 38 (53%) | 0.013 |
| Adv CRN*, n (%) | 48 (28%) | 15 (21%) | 0.27 |
| CRC/HGD, n (%) | 4 (2.3%) | 3 (4.2%) | 0.68 |
| Any SSA/P, n (%) | 36 (21%) | 8 (11%) | 0.10 |
| Non-neoplastic hemorrhagic lesionsα, n (%) | 9 (5%) | 6 (8%) | 0.39 |
α
Includes bleeding hemorrhoids, solitary rectal ulcer, new inflammatory bowel disease, ileitis, and new radiation proctopathy
*
Includes CRC, any lesion ≥10mm, HGD any size, and TVA any size
CRC, colorectal cancer; CRN, colorectal neoplasia; HGD, high-grade dysplasia; HP, hyperplastic polyp; SSA/P, sessile serrated adenoma/polyp