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. 2023 Jun 30;12(27):2301033. doi: 10.1002/adhm.202301033

Table 1.

Parameters of drugs pharmacokinetics in pigs plasma

PK Parameters Amoxicillin Levodopa
Control group Test group Control group Test group
T/2 (h) 1.33 ± 0.56 15.28 ± 14.85* 1.19 ± 0.65 5.95 ± 1.52*
Tmax (h) 3.33 ± 0.58 5 ± 0* 3.33 ± 0.58 5.67 ± 2.08*
Cmax(ng/mL) 2905.13 ± 546.33 1573.6 ± 638.64* 14 495.33 ± 9244.42 9633.3 ± 3734.54*
MRT (h) 4.3 ± 0.26 12.33 ± 5.5* 4.76 ± 0.72 10.98 ± 2.46*
AUC (ng/mL*h) 7732.25 ± 2418.25 7092.57 ± 1209.64 37 878.32 ± 11 330.11 84 626.71 ± 60 445.21*
*

P < 0.05, compared with control group, which demonstrates that differences are statistically significant, Independent sample T‐test.