Table 1.
PK Parameters | Amoxicillin | Levodopa | ||
---|---|---|---|---|
Control group | Test group | Control group | Test group | |
T/2 (h) | 1.33 ± 0.56 | 15.28 ± 14.85* | 1.19 ± 0.65 | 5.95 ± 1.52* |
Tmax (h) | 3.33 ± 0.58 | 5 ± 0* | 3.33 ± 0.58 | 5.67 ± 2.08* |
Cmax(ng/mL) | 2905.13 ± 546.33 | 1573.6 ± 638.64* | 14 495.33 ± 9244.42 | 9633.3 ± 3734.54* |
MRT (h) | 4.3 ± 0.26 | 12.33 ± 5.5* | 4.76 ± 0.72 | 10.98 ± 2.46* |
AUC (ng/mL*h) | 7732.25 ± 2418.25 | 7092.57 ± 1209.64 | 37 878.32 ± 11 330.11 | 84 626.71 ± 60 445.21* |
P < 0.05, compared with control group, which demonstrates that differences are statistically significant, Independent sample T‐test.