Table 4.
Contents of hepatic bile acids after LR extract and BLR extract consumption (ng/mg).
| Liver |
ND | HFD | HFD+LL | HFD+LM | HFD+LH | HFD+BL | HFD+BM | HFD+BH | HFD+XZK | ||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BA | Source | Strecture | |||||||||
| α-MCA | P-BA | U-BA | 0.87 ± 0.03de | 0.69 ± 0.02e | 0.80 ± 0.05de | 0.98 ± 0.03d | 1.45 ± 0.05c | 1.51 ± 0.08c | 2.00 ± 0.03b | 3.04 ± 0.06a | 1.27 ± 0.05c |
| β-MCA | P-BA | U-BA | 3.30 ± 0.19c | 2.63 ± 0.14de | 2.06 ± 0.14e | 2.10 ± 0.12e | 3.13 ± 0.10d | 4.19 ± 0.20bc | 5.31 ± 0.20a | 5.02 ± 0.24 ab | 3.27 ± 0.21cd |
| CA | P-BA | U-BA | 0.17 ± 0.01e | 3.14 ± 0.12bc | 2.58 ± 0.11c | 2.11 ± 0.09cd | 3.54 ± 0.11 ab | 3.33 ± 0.12 ab | 2.58 ± 0.09c | 3.36 ± 0.13 ab | 2.28 ± 0.12cd |
| CDCA | P-BA | U-BA | 0.08 ± 0.02e | 2.19 ± 0.11d | 3.18 ± 0.13bc | 2.78 ± 0.05c | 3.82 ± 0.12b | 3.23 ± 0.12bc | 4.20 ± 0.11a | 4.34 ± 0.14a | 3.13 ± 0.09bc |
| DHCA | P-BA | U-BA | ND | ND | ND | ND | ND | ND | ND | ND | ND |
| TCA | P-BA | T-BA | 16.18 ± 1.06d | 24.42 ± 1.82bcd | 20.35 ± 2.20cd | 24.99 ± 1.65bcd | 30.25 ± 2.47bc | 32.96 ± 1.42b | 44.49 ± 1.70a | 44.46 ± 1.56a | 31.89 ± 2.01b |
| TUDCA | P-BA | T-BA | 0.42 ± 0.06d | 1.03 ± 0.07cd | 0.75 ± 0.06d | 0.87 ± 0.11d | 0.88 ± 0.14d | 1.54 ± 0.16bc | 2.00 ± 0.27b | 3.22 ± 0.10a | 3.56 ± 0.18a |
| T(α+β)MCA | P-BA | T-BA | 7.58 ± 0.68d | 11.57 ± 0.83d | 7.34 ± 0.66d | 16.94 ± 1.33c | 18.92 ± 0.56bc | 21.58 ± 1.35bc | 23.91 ± 1.14b | 36.29 ± 1.17a | 17.77 ± 1.18c |
| GCDCA | P-BA | G-BA | ND | ND | ND | ND | ND | ND | ND | ND | ND |
| GCA | P-BA | G-BA | 0.03 ± 0.01cd | 0.10 ± 0.01a | 0.01 ± 0.00d | 0.01 ± 0.00d | 0.07 ± 0.01 ab | 0.02 ± 0.01cd | 0.04 ± 0.01bcd | 0.06 ± 0.01bc | 0.05 ± 0.01bcd |
| GDCA | S-BA | G-BA | ND | ND | ND | ND | ND | ND | ND | ND | ND |
| GUDCA | S-BA | G-BA | ND | ND | ND | ND | ND | ND | ND | ND | ND |
| TLCA | S-BA | T-BA | 0.01 ± 0.01a | 0.03 ± 0.01a | 0.00 ± 0.00a | 0.01 ± 0.00a | 0.01 ± 0.01a | 0.01 ± 0.00a | 0.02 ± 0.00a | 0.02 ± 0.00a | 0.02 ± 0.00a |
| TDCA | S-BA | T-BA | 1.32 ± 0.10cd | 1.66 ± 0.99c | 0.89 ± 0.06d | 1.07 ± 0.08cd | 1.42 ± 0.16cd | 2.98 ± 0.11 ab | 3.09 ± 0.11 ab | 2.60 ± 0.13b | 3.37 ± 0.21a |
| THDCA | S-BA | T-BA | 0.28 ± 0.02d | 1.00 ± 0.09cd | 0.51 ± 0.14d | 0.66 ± 0.08d | 0.89 ± 0.07d | 0.96 ± 0.12cd | 1.63 ± 0.21bc | 2.71 ± 0.11a | 1.99 ± 0.25b |
| LCA | S-BA | U-BA | ND | ND | ND | ND | ND | ND | ND | ND | ND |
| HDCA | S-BA | U-BA | 0.00 ± 0.00a | 0.00 ± 0.00a | 0.00 ± 0.00a | 0.00 ± 0.00a | 0.00 ± 0.00a | 0.01 ± 0.00a | 0.01 ± 0.00a | 0.00 ± 0.00a | 0.00 ± 0.00a |
| DCA | S-BA | U-BA | ND | ND | ND | ND | ND | ND | ND | ND | ND |
| UDCA | S-BA | U-BA | 0.02 ± 0.00c | 0.05 ± 0.00b | 0.02 ± 0.00c | 0.01 ± 0.00c | 0.05 ± 0.01b | 0.03 ± 0.00bc | 0.05 ± 0.01b | 0.09 ± 0.01a | 0.02 ± 0.01bc |
| Total P-BA | 28.64 ± 0.61g | 45.77 ± 2.20ef | 37.08 ± 1.47 fg | 50.77 ± 2.91de | 62.16 ± 2.84cd | 68.35 ± 3.23c | 84.54 ± 3.44b | 99.83 ± 3.71a | 63.22 ± 2.92c | ||
| Total S-BA | 1.64 ± 0.10cd | 2.74 ± 0.17c | 1.42 ± 0.14d | 1.74 ± 0.16cd | 2.38 ± 0.23cd | 3.98 ± 0.02b | 4.79 ± 0.23 ab | 5.43 ± 0.03a | 5.40 ± 0.44a | ||
| Total U-BA | 4.45 ± 0.19cd | 8.70 ± 0.15de | 8.64 ± 0.18e | 7.97 ± 0.07de | 12.09 ± 0.05c | 12.29 ± 0.17b | 14.15 ± 0.20a | 15.90 ± 0.29a | 9.97 ± 0.24c | ||
| Total C-BA | 25.83 ± 0.41g | 39.81 ± 2.41ef | 29.86 ± 1.52 fg | 44.53 ± 3.05de | 52.45 ± 3.07cd | 60.04 ± 3.39c | 75.18 ± 3.73b | 89.36 ± 3.46a | 58.65 ± 3.15c | ||
| Total BA | 30.28 ± 0.56g | 48.51 ± 2.32ef | 38.50 ± 1.49 fg | 52.51 ± 3.00de | 64.53 ± 3.04cd | 72.33 ± 3.22c | 89.33 ± 3.65b | 105.26 ± 3.74a | 68.63 ± 3.35c | ||
Note: All data in the table are shown as mean ± SEM (n = 8). Means with different letters in the same row are significantly different using one-way ANOVA followed by the Duncan's test, P < 0.05.