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. 2023 Aug 28;5(12):100897. doi: 10.1016/j.jhepr.2023.100897

Table 3.

UK key performance indicator (KPI) results comparing centres with multidisciplinary services (MD) vs. centres without multidisciplinary services (no MD).

Management of people with, or at risk of, NAFLD before the gastroenterology or liver clinic N No MD (%) N MD (%) p value
1. Services should have an agreed local clinical pathway for the investigation of suspected liver disease that includes an assessment for liver fibrosis using available non-invasive liver fibrosis tests 13 69.2 21 90.5 0.02
2. Individuals referred to secondary care with suspected NAFLD should have their non-invasive fibrosis staging (e.g. FIB-4 score or NAFLD fibrosis score) documented in the referral letter.
298
26.2
471
28.7
0.51
Investigations and management in secondary care





3. People with NAFLD should have their weight and BMI documented 298 69.8 471 75.8 0.08
4. People with NAFLD should have an alcohol history documented and advice given, where appropriate
 a) Documented 298 88.9 471 91.5 0.26
 b) Advice given where appropriate 165 33.3 307 57.7 <0.01
5. People with NAFLD should have a smoking history documented and advice given, where appropriate
 a) Documented 298 43.6 471 62.0 <0.01
 b) Advice given where appropriate 92 12.0 161 14.3 0.70
6. People with NAFLD should undergo liver fibrosis staging using available non- invasive tests or liver biopsy 298 69.5 471 85.4 <0.01
 Transient elastography/Fibroscan requested/performed 298 63.1 471 80.9 <0.01
 ELF requested 298 3.4 471 7.6 0.02
 Ultrasound Acoustic Radiation Force Impulse (ARFI) requested 298 0.3 471 0.6 >0.99
 NFS score calculated 298 4.4 471 0.8 <0.01
 FIB-4 score calculated 298 17.8 471 17.6 >0.99
 Liver biopsy 298 6.4 471 6.8 0.88
7. Patients with NAFLD should be screened for T2DM 298 23.2 471 39.1 <0.01
 Diabetic patients advised on optimising diabetes control 117 29.9 217 42.4 0.03
8. People with NAFLD should be screened for hypertension 298 15.4 471 21.4 0.05
 Patients with hypertension advised on optimising blood pressure control 135 13.3 247 19.4 0.16
9. Patients with NAFLD should have weight loss advice documented including objective goals for weight change and physical activity.
 (a) Assessment of physical activity 298 28.2 471 44.8 <0.01
 (b) Assessment of dietary habits 298 31.2 471 42.3 <0.01
 (c) Exercise advice given 283 45.2 447 61.7 0.06
 (d) Weight loss target given 278 25.5 444 36.5 <0.01
 (e) Tailored dietary advice 278 28.4 452 40.7 <0.01
10. Patients who are at increased cardiovascular risk (T2DM and/or QRISK-3 >10%) should be offered statin treatment in accordance with NICE guidelines. 137 3.6 197 13.2 <0.01
11. Patients should be provided with written information about NAFLD and weight management and/or signposted to credible information sources. 248 9.3 434 24.7 <0.01

Bold values signifies significant p <0.05.

ELF, Enhanced Liver Fibrosis; FIB-4, Fibrosis 4; MD, percentage of positive responses for each KPI in hospitals with multidisciplinary services; N, total number of recorded responses for each KPI; NAFLD, non-alcoholic fatty liver disease; NFS, NAFLD fibrosis score; NICE, National Institute for Health and Care Excellence; no MD (multidisciplinary services), percentage of positive responses for each KPI in hospitals without multidisciplinary services; T2DM, type 2 diabetes mellitus.