TABLE 1.

Biomarker combinations ranked according to their value of the negative log-likelihood using the combined data from the three study sites

No. of biomarkers combined	Best combination [marker(s)] Log-likelihood, AUC for logistic regression	Second best combination [marker(s)] Log-likelihood, AUC for logistic regression	Third best combination [marker(s)] Log-likelihood, AUC for logistic regression
1	[I-309] 210, 0.87	[SYWC] 213, 0.86	[MIG] 244, 0.83
2	[I-309, SYWC] 189, 0.88	[I-309, kallistatin] 199, 0.87	[kallistatin, SYWC] 201, 0.88
3	[I-309, SYWC, kallistatin] 182, 0.90	[I-309, SYWC, ApoA1] 188, 0.89	[I-309, SYWC, NPSPLA2] 189, 0.89
4	[I-309, SYWC, kallistatin, C9] 179, 0.89	[I-309, SYWC, kallistatin, NPSPLA2] 180, 0.90	[I-309, SYWC, kallistatin, ApoA1] 181, 0.90
5	[I-309, SYWC, kallistatin, C9, LBP] 174, 0.90	[I-309, SYWC, kallistatin, SAA, C9] 175, 0.89	[I-309, SYWC, kallistatin, C9, NPSPLA2] 175, 0.90
6	[I-309, SYCW, kallistatin, C9, LBP, ApoA1] 174, 0.90	[I-309, SYWC, kallistatin, SAA, C9, LBP] 174, 0.89	[I-309, SYWC, kallistatin, C9, NPSPLA2, SAA] 174, 0.90
12	[NPSPLA2, SYWC, C9, LBP, CRP, SAA, kallistatin, ferritin, IP-10, I-309, MIG, ApoA1] 172, 0.89