Fig. 1.

Evidence-based recommendations for female-specific pharmacotherapy, based on three pillars: sex-specific dosing, hormonal replacement, and correction of prolactin levels. Abbreviations: AP, antipsychotic; PANSS, Positive and Negative Syndrome Scale; TDM, therapeutic drug monitoring; COC, combined oral contraceptive; HC, hormonal contraceptive; ARI, aripiprazole. Footnotes: ¹Based on Schoretsanitis et al. [77•]. ²Based on the Stages of Reproductive Aging Workshop (STRAW + 10). ³Should be based on shared decision, primarily led by preference and/or current use of the participant. ⁴Amisulpride, asenapine, chlorpromazine, haloperidol, lurasidone, olanzapine, paliperidone, and risperidone