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. 2023 Sep 27;25(11):683–698. doi: 10.1007/s11920-023-01456-2

Table 7.

Intervention updates

Key publications Sample Key findings
Devoe et al. (2020) [137] Meta-analysis: 38 studies CBT associated with reduction in conversion
Mei et al. (2021) [135] Meta-analysis: 26 studies CBT was associated with a reduction in incidence at 12 months
Kuharic et al. (2019) [136] Cochrane Review: 20 studies No clear differences between treatments in prevention of conversion, small evidence of Omega-3 in preventing transition to psychosis but low statistical power
Zhang et al. (2022) [141] SHARP: CHR (N = 210), CHR-C (N = 56), CHR-NC (N = 154) Antipsychotic treatment (N = 151) vs no antipsychotic treatment (N = 59) had no effect on conversion rate in a naturalistic design

SHARP Shanghai at Risk for Psychosis, CHR clinical high risk, CHR-C clinical high risk converted, CHR-NC CHR non-converted, CBT cognitive behavioral therapy