Table 2.
Causes for infertility
| pSS (n = 24) | Healthy controls (n = 96) | P value | |
|---|---|---|---|
| Causes for infertility | |||
| Primary infertility, n (%) | 6 (25.0) | 19 (19.8) | 0.57 |
| Recurrent spontaneous abortion, n (%) | 4 (16.7) | 0 (0) | 0.001 |
| Obstruction of fallopian tubes, n (%) | 2 (8.3) | 29 (30.2) | 0.04 |
| PCOS, n (%) | 1 (4.2) | 2 (2.1) | > 0.99 |
| Endometriosis, n (%) | 1 (4.2) | 2 (2.1) | > 0.99 |
| Hereditary disease, n (%) | 1 (4.2) | 0 (0) | 0.20 |
| Cervical factors, n (%) | 0 (0) | 1 (1.0) | > 0.99 |
| Scarred uterus, n (%) | 0 (0) | 9 (9.4) | 0.20 |
| Fetal chromosomal abnormalities, n (%) | 0 (0) | 3 (3.1) | 0.61 |
| Male factor, n (%) | 2 (8.3) | 19 (19.8) | 0.24 |
| Unexplained, n (%) | 13 (54.2) | 28 (29.2) | 0.02 |
| Procedure | |||
| IVF-ET, n (%) | 22 (91.7) | 73 (76.0) | 0.09 |
| ICSI, n (%) | 1 (4.2) | 13 (13.5) | 0.30 |
| IUI, n (%) | 0 (0) | 4 (4.2) | 0.58 |
| PGT, n (%) | 1 (4.2) | 6 (6.3) | > 0.99 |
ART assisted reproductive therapy, ICSI intracytoplasmic sperm injection, IUI intrauterine insemination, IVF-ET in vitro fertilization-embryo transfer, PCOS polycystic ovary syndrome, PDT preimplantation genetic testing, pSS primary Sjögren’s syndrome