Table 1. Baseline characteristics of overall and propensity-score matched population.
| Total study population | Propensity-score matched population | ||||||
|---|---|---|---|---|---|---|---|
| Early AVR (n=121) | Conservative care (n=160) | SMD | Early AVR (n=121) | Conservative care (n=121) | SMD | ||
| Age (years) | 75.1±9.8 | 77.1±9.7 | 0.206 | 75.1±9.8 | 76.5±10.0 | 0.141 | |
| Female sex | 63 (52.1) | 105 (65.6) | 0.278 | 63 (52.1) | 72 (59.5) | 0.150 | |
| Body surface area (m2) | 1.63±0.18 | 1.59±0.16 | 0.241 | 1.63±0.18 | 1.61±0.16 | 0.102 | |
| Body mass index (kg/m2) | 24.0±3.8 | 23.5±3.8 | 0.122 | 24.0±3.8 | 23.9±3.7 | 0.031 | |
| Hypertension | 74 (61.2) | 99 (61.9) | 0.015 | 74 (61.2) | 73 (60.3) | 0.017 | |
| Diabetes on insulin | 19 (15.7) | 14 (11.6) | 0.150 | 19 (15.7) | 14 (11.6) | 0.120 | |
| Chronic kidney disease | 44 (36.4) | 63 (39.4) | 0.062 | 44 (36.4) | 43 (35.5) | 0.017 | |
| On dialysis | 8 (6.6) | 10 (6.2) | 0.015 | 8 (6.6) | 7 (5.8) | 0.034 | |
| Coronary artery disease | 14 (11.6) | 24 (15.0) | 0.101 | 14 (11.6) | 15 (12.4) | 0.025 | |
| Peripheral artery disease | 6 (5.0) | 11 (6.9) | 0.081 | 6 (5.0) | 7 (5.8) | 0.037 | |
| Old cerebrovascular accident | 3 (2.5) | 10 (6.2) | 0.185 | 3 (2.5) | 3 (2.5) | <0.001 | |
| Atrial fibrillation | 9 (7.4) | 18 (11.2) | 0.131 | 9 (7.4) | 11 (9.1) | 0.060 | |
| Pacemaker implantation | 1 (0.8) | 3 (1.9) | 0.091 | 1 (0.8) | 1 (0.8) | <0.001 | |
| Chronic lung disease | 12 (9.9) | 15 (9.4) | 0.018 | 12 (9.9) | 11 (9.1) | 0.028 | |
| Chronic liver disease | 3 (2.5) | 4 (2.5) | 0.001 | 3 (2.5) | 4 (3.3) | 0.049 | |
| Bicuspid aortic valve | 15 (12.4) | 15 (9.4) | 0.097 | 15 (12.4) | 12 (9.9) | 0.079 | |
| Symptoms | 0.182 | 0.137 | |||||
| NYHA class I–II | 105 (86.8) | 128 (80.0) | 105 (86.8) | 99 (81.8) | |||
| NYHA class III–IV | 16 (13.2) | 32 (20.0) | 16 (13.2) | 22 (18.2) | |||
| Estimated PASP | 30.0 (25.0–35.0) | 31.0 (26.5–39.0) | 0.235 | 30.0 (25.0–35.0) | 31.0 (27.0–36.0) | 0.156 | |
| EuroSCORE II (%) | 1.60 (1.06–2.21) | 1.80 (1.34–2.62) | 0.286 | 1.60 (1.06–2.21) | 1.79 (1.29–2.39) | 0.159 | |
Values are presented as number (%), mean±standard deviation or median (range).
AVR = aortic valve replacement; EuroSCORE = European System for Cardiac Operative Risk Evaluation; NYHA = New York Heart Association, PASP = pulmonary artery systolic pressure; SMD = standardized mean difference.