Table 3. Clinical outcomes.

Events		Number of events (%/year)		HR (95% CI)	p value
		Early AVR	Conservative care
Overall		121	121
	Primary outcome	18 (5.0)	30 (10.1)	0.52 (0.29–0.93)	0.028
	All-cause death	9 (2.5)	16 (5.0)	0.51 (0.23–1.16)	0.110
	Heart failure hospitalization	9 (2.5)	18 (6.0)	0.43 (0.19–0.95)	0.037
vs. Delayed AVR		121	43
	Primary outcome	18 (5.0)	13 (7.0)	0.60 (0.29–1.22)	0.159
	All-cause death	9 (2.5)	4 (2.0)	0.92 (0.28–3.01)	0.895
	Heart failure hospitalization	9 (2.5)	9 (4.9)	0.46 (0.18–1.16)	0.099
vs. Conservative care		121	78
	Primary outcome	18 (5.0)	17 (15.1)	0.47 (0.24–0.92)	0.027
	All-cause death	9 (2.5)	12 (10.0)	0.34 (0.14–0.83)	0.017
	Heart failure hospitalization	9 (2.5)	9 (7.9)	0.42 (0.16–1.06)	0.067

AVR = aortic valve replacement; CI = confidence interval; HR = hazard ratio.