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. 2023 Nov 16;6:251. doi: 10.1038/s42004-023-01050-w

Table 2.

Protonation constants and stability constants of Ligand-T, Ligand-L and DOTA18.

log KiH Ligand-Ta Ligand-La DOTAb
log K1H 11.30 (0.07) 13.53 (0.25) 11.14
log K2H 11.10 (0.09) 10.25 (0.12) 9.69
log K3H 10.30 (0.28) 9.90 (0.20) 4.85
log K4H 6.08 (0.30) 4.63 (0.19) 3.95
∑log KiH 38.78 38.31 29.62
log KGdL 30.01b / 25.58(32)

aI = 1.0 M NMe4Cl, at 25 °C.

bI = 1.0 M KCl, at 25 °C, where KiH = [HiL]/[Hi-1L][H+], SD were shown in brackets.

bI = 0.1 M NMe4Cl, at 25 °C31.