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. 2023 Nov 16;14:7421. doi: 10.1038/s41467-023-42997-7

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — a Age distribution in these seven studies. b Gender proportions of these seven studies. c Body mass index distribution in four studies with this information available. d Spine plots for response “CR/PR” versus no response “SD/PD”. e Survival curves for OS by cancer types. f Sankey plot for irAEs, response, and whether progression-free survival longer than 12 months. g Survival curves for OS of response “CR/PR” and no response “SD/PD” groups. P values from log-rank tests are shown in survival plots. irAEs immune-related adverse events, PFS progression-free survival, OS overall survival.