Table 4.
Data of acyclovir transferred through modified non-everted intestinal sac (n = 3).
| r2 | Intercept × 10−3 | Papp (cm/s) × 10−6 | Total penetration % | DAE% | |
|---|---|---|---|---|---|
| Pure drug | 0.999 | 1.3 | 10 (± 1.84) | 16.055 (± 0.92) | 100.000 |
| 15%span 60 | 0.996 | 2.7 | 20 (± 1.35) | 35.630 (± 1.08) | 221.924 |
| 20%span 60 | 0.994 | 2.7 | 30 (± 1.66) | 41.125 (± 2.65) | 256.151 |
| 25%span 60 | 0.997 | 8.2 | 20 (± 2.79) | 54.960 (± 3.93) | 342.323 |
DAE % = drug absorption enhancement percent compared to the pure drug.