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. 2023 Oct 18;26(11):108243. doi: 10.1016/j.isci.2023.108243

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© 2023 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Changes in VP-LDCV trafficking dynamics in response to acute changes in VP neuronal activity

(A–C) Plots of dendritic LDCV mean speed (left), max speed (middle), and incidence of anterograde travel (right) under basal conditions and in response to (A) TTX (1 μM), (B) NMDA (10 μM), and (C) Mannitol (0.2%). Numbers at the top center of each panel represent n values (animals | dendrites | LDCVs). %Anterograde travel individual points represent 1 process. ∗∗∗∗p < 0.0001, unpaired t test (Mean and Max vesicle speed), paired t test (%Anterograde Travel).