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. 2023 Oct 18;26(11):108243. doi: 10.1016/j.isci.2023.108243

Figure 5.

Figure 5

Changes in VP-LDCV trafficking dynamics in response to chronic osmotic challenges

(A) Violin plots of mean LDCV speed in dendrites (left) and axons (right) under euhydrated control conditions, 48 h of water deprivation (WD), and 7 days salt loading (SL). ∗∗∗p < 0.0001, One Way ANOVA, Šidák multiple comparisons test.

(B) Violin plots of max LDCV speed in dendrites (left) and axons (right) under euhydrated control conditions, 48 h of water deprivation (WD), and 7 days salt loading (SL). Max LDCV speed of dendrites (left) and axons (right) compared under control conditions, WD, and SL. ∗∗∗p < 0.0001, One Way ANOVA, Šidák multiple comparisons test.

(C) Summary of directionality of all tracked LDCVs under control euhydrated conditions, WD, and SL in dendrites and axons (∗∗p < 0.01, two-way ANOVA). The only within-groups difference was between control and SL dendrites (∗p < 0.05, Šidák multiple comparisons test). Numbers below each group represent n values (processes).

(D) Kernel density distributions of mean speed of VP-LDCV anterograde vs. retrograde traveling in control euhydrated, WD, and SL conditions from dendrites (left) and axons (right). Numbers in each plot represent n values, color coded to correspond to experimental group (LDCVs).