Figure 3.

The Crucial Role of Single-cell Sequencing in Exploring Ovarian Cancer Heterogeneity. Heterogeneity Single-cell sequencing technology plays a vital role in unraveling the heterogeneity of ovarian cancer. It enables precise discrimination of tumor heterogeneity among different patients and distinguishes heterogeneity between distinct lesions within the same patient, such as primary and metastatic lesions. Importantly, given the diverse cellular composition within tumor tissues, single-cell sequencing also identifies cellular heterogeneity within the tumor microenvironment. Furthermore, the integration of multi-omicss data, including genomics, transcriptomics, proteomics, and epigenomics, provides a comprehensive understanding of tumor molecular characteristics and underlying developmental mechanisms.