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. 2023 Nov 2;14:1268785. doi: 10.3389/fneur.2023.1268785

Table 2.

Characteristics of included disease-specific HRQoL questionnaires.

Questionnaire Number of items Score Subscales Recall period MCID
Ear symptoms Hearing function Mental health Health service utilization Lifestyle and work impact / social Others
CES Chronic Ear Survey 13 0–100 4-/6- point Likert scale graphic file with name fneur-14-1268785-i0001.jpg graphic file with name fneur-14-1268785-i0002.jpg Absent graphic file with name fneur-14-1268785-i0003.jpg graphic file with name fneur-14-1268785-i0004.jpg No recall period mentioned, with the exception of: Unknown
Ear discharge, pain, odor Hearing loss Doctor visits antibiotic use Water avoidance; Interference with social life ear drainage and health service utilization 6 months, social impact 4 weeks.
Dizziness, tinnitus
COMOT-15 Chronic Otitis Media Outcome Test 15 0–100 6-point Likert scale graphic file with name fneur-14-1268785-i0005.jpg graphic file with name fneur-14-1268785-i0006.jpg graphic file with name fneur-14-1268785-i0007.jpg graphic file with name fneur-14-1268785-i0008.jpg Absent graphic file with name fneur-14-1268785-i0009.jpg 6 months Unknown
Ear discharge, pain, pressure, tinnitus Hearing loss, situational hearing problems Related to hearing loss Doctor visits Overall QoL, headache
Odor Dizziness/vertigo
COMQ-12 Chronic Otitis Media Questionnaire 12 0–60 6-point Likert scale graphic file with name fneur-14-1268785-i0010.jpg graphic file with name fneur-14-1268785-i0011.jpg graphic file with name fneur-14-1268785-i0012.jpg graphic file with name fneur-14-1268785-i0013.jpg graphic file with name fneur-14-1268785-i0014.jpg 6 months Unknown values <8 indicate a normal HRQoL in healthy population (44)
Ear discharge, odor, discomfort, dizziness, tinnitus Situational hearing problems Overall impact Doctor visits, Antibiotic use Water avoidance, Interference with social/work
ZCMEI-21 Zurich Chronic Middle Ear Inventory 21 0–84 5-point Likert scale graphic file with name fneur-14-1268785-i0015.jpg graphic file with name fneur-14-1268785-i0016.jpg graphic file with name fneur-14-1268785-i0017.jpg graphic file with name fneur-14-1268785-i0018.jpg graphic file with name fneur-14-1268785-i0019.jpg 2 weeks health service utilization 6 months MCID: 5.3
Ear discharge, Pain, pressure, balance, problems, tinnitus Hearing loss, Situational hearing problems Anxiety Doctor visits, antibiotic use Water avoidance, interference with social/work
Odor

HRQoL, Health-Related Quality of Life; MCID, Minimal Clinically Important Difference. In all questionnaires higher scores indicate poorer HRQoL. Except for CES in which higher scores indicate better HRQoL. The green part of a circle indicates the portion of the questionnaire which is covered by the specific subscale. All terms to describe symptoms or subscales are abstracted from the questionnaires. Red blocks indicate the absence of a specific factor or whole subscale in the questionnaire.