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. 2023 Oct 31;2:1153115. doi: 10.3389/fnimg.2023.1153115

Table 6.

Symptom longevity relative to FA of corpus callosum regions.

Percent participants with resolved symptoms
6 months after injury 12 months after injury
Symptom p -value p -value CI Score Statistic Lower 1/3 Middle 1/3 Upper 1/3 Lower 1/3 Middle 1/3 Upper 1/3
Headache (n = 420)
Total 0.83 0.75 0.91 0.08 48 45 47 64 52 55
Anterior 0.43 0.36 0.49 0.29 45 47 46 59 58 54
Mid-body 0.50 0.43 0.57 0.30 39 61 45 57 63 51
Posterior 0.74 0.66 0.82 0.14 44 50 50 63 54 55
Balance (n = 310)
Total 0.56 0.49 0.64 −0.16 47 48 42 66 52 49
Anterior 0.90 0.81 0.98 −0.07 41 54 40 59 62 45
Mid-body 0.42 0.35 0.49 0.30 38 54 47 55 69 54
Posterior 0.45 0.39 0.52 0.28 46 47 46 60 54 51
Cognitive (n = 325)
Total 0.01 < 0.01 0.03 0.73 37 36 59 54 44 64
Anterior < 0.01 < 0.01 0.01 0.95 34 53 49 54 57 55
Mid-body 0.03 0.02 0.06 0.77 36 54 44 47 63 54
Posterior 0.91 0.83 0.99 0.05 42 31 51 64 46 56
Fatigue (n = 75)
Total 0.10 0.07 0.14 0.13
Anterior 0.50 0.43 0.57 0.06
Mid-body 0.86 0.78 0.94 0.01
Posterior 0.07 0.04 0.11 0.20
Anxiety (n = 123)
Total 0.14 0.10 0.19 0.18
Anterior 0.53 0.46 0.60 0.10
Mid-body 0.14 0.10 0.18 0.23
Posterior 0.15 0.11 0.20 0.20
Depression (n = 105)
Total 0.17 0.13 0.22 0.17
Anterior 0.20 0.16 0.26 0.17
Mid-body 0.35 0.29 0.42 0.16
Posterior 0.04 0.02 0.06 0.29
Emotional lability (n = 66)
Total 0.09 0.06 0.13 0.15
Anterior 0.18 0.13 0.23 0.13
Mid-body 0.11 0.07 0.15 0.19
Posterior 0.01 < 0.01 0.03 0.26

The permutation-based p-value and its 95% confidence interval (ci), and log rank score statistics are provided for each combination of region and symptom. The rows with a p-value < 0.05 are in bold. P-values were not adjusted for multiple comparisons. For tertiles with sample size >15, the percent of participants with resolved symptoms is reported at 6 months and 12 months, based on Turnbull intervals.