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. 2023 Nov 3;14:1279448. doi: 10.3389/fphar.2023.1279448

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Copyright © 2023 Zhou, Liu, Lin, Shi, Zeng, Guan, Ma, Zeng, Zhong and Xu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Correlations between distinct genera and clinical parameters and function prediction of distinct genera. Spearman’s correlation analysis of distinct genera and clinical parameters (A), *p < 0.05, **p < 0.01, ***p < 0.001. Co-occurrence network graph of the main distinct genera and clinical parameters (B), |r| > 0.45, p < 0.05. Genera are labeled with circles, while clinical parameters are labeled with diamonds. The nodes with solid or dashed boundaries were enriched in patients with or without sarcopenia, respectively. Positive correlations are shown by gray and solid connecting lines, whereas negative correlations are represented by yellow and dashed connecting lines, and thicker lines indicate higher correlation values. The Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways with significant differences in function prediction using Statistical Analysis of Metagenomic Profiles (STAMP) software (C).