Figure 1. Cumulative event curves for clinical outcomes stratified by the method for the definition of PPM.

A, B & C) Clinical outcomes according to measured PPM. D, E & F) Clinical outcomes according to predicted PPM_THV. Hazard ratios and p-values were calculated with the use of Cox proportional hazards models. CI: confidence interval; HR_adjusted: adjusted hazard ratio; PPM: prosthesis-patient mistmatch; PPM_THV: PPM defined by the normal reference values of EOA for each size and model of implanted transcatheter heart valve; TAVR: transcatheter aortic valve replacement