Table 1.
Characteristics and predictors for analysis in both subsamples.
| Less than three months (n = 93) | More than three months (n = 20) | p value | Effect size (r) | |||
|---|---|---|---|---|---|---|
| Median (IQR) | Range (Min-Max) | Median (IQR) | Range (Min-Max) | |||
| Age [years] | 60 (52–69.5) | 20–85 | 61.5 (54–70) | 29–78 | 0.596 | 0.05 |
| BMI [kg/m2] | 20.3 (17.4–22.7) | 12.5–29.3 | 18.7 (17.2–21.1) | 14.4–28 | 0.266 | 0.11 |
| Bili T0 [mg/dl] | 0.4 (0.3–0.8) | 0.1–11.5 | 0.4 (0.3–0.8) | 0.1–2.9 | 0.699 | 0.04 |
| Bili T1 [mg/dl] | 0.4 (0.3–1) | 0.1–16.9 | 0.4 (0.3–0.5) | 0.2–5.1 | 0.522 | 0.07 |
| Albumin T0 [g/L] | 29.1 (25–34.2) | 17.8–44 | 29.7 (25–34.6) | 0.4–40 | 0.728 | 0.03 |
| Albumin T1 [g/L] | 25.6 (21.7–30.4) | 16–38.7 | 30.5 (26.9–32.5) | 23–37 | 0.014 | 0.27 |
| LDH T0 [U/L] | 194.5 (154–290.8) | 114–1878 | 205 (141–266) | 70–761 | 0.91 | 0.01 |
| LDH T1 [U/L] | 205 (159–311) | 41–630 | 206 (157–286.3) | 106–578 | 0.867 | 0.02 |
| GOT T0 [U/L] | 24.5 (18–42.5) | 6–332 | 25 (16–40) | 12–332 | 0.746 | 0.03 |
| GOT T1 [U/L] | 28 (19–44.8) | 11–324 | 26 (18.8–48.3) | 13–151 | 0.86 | 0.02 |
| GPT T0 [U/L] | 18 (11–33) | 5–289 | 14 (9.8–31.5) | 5–374 | 0.589 | 0.05 |
| GPT T1 [U/L] | 21.5 (14.3–41) | 8–251 | 33 (16.3–49.8) | 8–139 | 0.371 | 0.10 |
| gGT T0 [U/L] | 88.5 (41.5–236) | 10–2,884 | 66 (37–300) | 15–706 | 0.879 | 0.01 |
| gGT T1 [U/L] | 158.5 (75–385) | 13–2,190 | 155.5 (53.5–395) | 21–925 | 0.95 | 0.01 |
| AlkP T0 [U/L] | 111.5 (78.3–211.8) | 38–1,690 | 89 (71–309) | 58–826 | 0.734 | 0.03 |
| AlkP T1 [U/L] | 164 (103–338) | 41–2,496 | 164 (107.3–339) | 47–920 | 0.8 | 0.03 |
| CRP T0 [mg/dl] | 6.3 (2.9–13.2) | 0–46.4 | 5.1 (2.3–13.5) | 1–23 | 0.541 | 0.06 |
| CRP T1 [mg/dl] | 8.9 (4–18.9) | 0.4–41.3 | 7.2 (5.1–10.3) | 0.5–18.5 | 0.218 | 0.13 |
| Leukocytes T0 [G/L] | 8.1 (6.2–13.6) | 1.9–65.4 | 7.5 (4.6–10.2) | 1.4–18.8 | 0.192 | 0.12 |
| Leukocytes T1 [G/L] | 10.6 (7.2–13.8) | 2–99.6 | 7.3 (5.3–11.4) | 1.2–12.5 | 0.053 | 0.22 |
| Sodium T0 [mmol/L] | 136.5 (133–140) | 122–149 | 137 (134–138) | 131–145 | 0.903 | 0.01 |
| Sodium T1 [mmol/L] | 138 (132.5–141.5) | 126–154 | 137 (134–139.8) | 124–143 | 0.648 | 0.05 |
| Creatinine T0 [mg/dl] | 0.7 (0.6–1.1) | 0.3–4 | 0.6 (0.5–0.8) | 0.3–1.5 | 0.141 | 0.14 |
| Creatinine T1 [mg/dl] | 0.7 (0.5–1.4) | 0.2–6 | 0.7 (0.5–0.8) | 0.3–1.7 | 0.247 | 0.13 |
| Magnesium T0 [mmol/L] | 0.7 (0.7–0.9) | 0.4–1.3 | 0.7 (0.7–0.8) | 0.4–0.9 | 0.771 | 0.03 |
| Calcium T0 [mmol/L] | 2.1 (2–2.2) | 1.1–3.4 | 2.2 (2–2.3) | 1.9–2.8 | 0.282 | 0.10 |
| Potassium T0 [mmol/L] | 3.8 (3.4–4.1) | 2.6–6 | 3.9 (3.2–4.1) | 2.8–4.9 | 0.823 | 0.02 |
| Potassium T1 [mmol/L] | 4 (3.5–4.3) | 0.5–5.8 | 4.1 (3.8–4.4) | 3.2–6.4 | 0.301 | 0.11 |
| Urea T0 [mg/dl] | 19 (11.7–29.3) | 2–76 | 11 (9.3–20.5) | 3.9–34.3 | 0.016 | 0.23 |
| Uric Acid T0 [mg/dl] | 4.9 (3.4–8.3) | 1.2–26.4 | 4.1 (3.1–6.4) | 2–9 | 0.193 | 0.13 |
| CRP/albumin ratio T0 | 0.2 (0.1–0.5) | 0–1.9 | 0.2 (0.1–0.5) | 0–5.3 | 0.969 | 0.00 |
| CRP/albumin ratio T1 | 0.3 (0.1–0.8) | 0–1.9 | 0.3 (0.1–0.4) | 0–0.8 | 0.092 | 0.18 |
| Bili diff | 0 (− 0.2 - 0.3) | −10.6 - 14.4 | 0 (− 0.2–0.1) | −1.1 - 3.3 | 0.499 | 0.08 |
| Albumin diff | −4.4 (− 8.2 - 1.2) | −18.7 - 11 | −0.1 (− 4.1–4.1) | −8.1 - 28.6 | 0.037 | 0.24 |
| LDH diff | 6.5 (− 28–52.8) | −285 - 245 | −9.5 (− 41.5–29.8) | −85 - 176 | 0.383 | 0.10 |
| GOT diff | 3 (− 4–13.3) | −238 - 247 | 2.5 (− 5.8–12.3) | −181 - 28 | 0.57 | 0.06 |
| GPT diff | 3 (− 6–18) | −175 - 193 | 3 (− 6–23) | −235 - 37 | 0.882 | 0.02 |
| gGT diff | 54.5 (− 14.3–174.3) | −1,386 - 1341 | 77 (− 4–215) | −188 - 307 | 0.797 | 0.03 |
| AlkP diff | 37 (1–92) | −233 - 1085 | 29 (− 14–113.3) | −65 - 354 | 0.639 | 0.05 |
| CRP diff | 2.6 (− 2.4–7.4) | −30.8 - 35.2 | 2 (− 2.8–4.2) | −12.6 - 6.9 | 0.165 | 0.15 |
| Leukocytes diff | 1.5 (− 3.5–5.9) | −41.5 - 34.3 | 1.3 (− 2.2–2.9) | −10.1 - 3.7 | 0.434 | 0.09 |
| Sodium diff | 0.5 (− 3–4.8) | −11 - 15 | 0 (− 2–3) | −12 - 8 | 0.656 | 0.05 |
| Creatinine diff | −0.1 (− 0.2–0.1) | −1.7 - 4.3 | 0 (− 0.2–0.2) | −0.4 - 0.7 | 0.745 | 0.04 |
| Potassium diff | 0.1 (− 0.3–0.6) | −2.9 - 2 | 0.2 (− 0.2–0.6) | −0.7 - 3.4 | 0.439 | 0.09 |
| CRP/albumin ratio diff | 0.1 (0–0.4) | −1.25 - 1.86 | 0.1 (− 0.2–0.1) | −5.1 - 0.3 | 0.059 | 0.21 |
Parameters with an effect size r > 0.2 are highlighted in bold. Diff = difference in the respective parameter from T0 to T1. BMI, body mass index. Bili, bilirubin. LDH, lactate dehydrogenase. GOT, serum glutamic oxaloacetic transaminase. GPT, serum glutamic pyruvic transaminase. gGT, gamma-glutamyl transferase. AlkP, alkaline phosphatase. CRP, C-reactive protein.