Table 1:
Baseline characteristics
| Characteristic | Entire Cohort | No Mental Health Disorder | Any Mental Health Disorder | p-value |
|---|---|---|---|---|
| Total | 13,244 | 11,150 | 2,094 | |
| Age at Diagnosis, yrs | ||||
| Mean (SD) | 78.7 (6.9) | 78.7 (6.9) | 79.1 (6.8) | 0.009 |
| Median (IQR) | 79 (11) | 78 (11) | 79 (10) | 0.006 |
| Sex | ||||
| Male | 6,256 (47.2%) | 5,545 (49.7%) | 711 (34.0%) | <0.0001 |
| Female | 6,988 (52.8%) | 5,605 (50.3%) | 1,383 (66.1%) | |
| Race * | ||||
| White | 12,468 (94.1%) | 10,453 (93.7%) | 2,015 (96.2%) | <0.0001 |
| Non-White | 776 (5.9%) | 697 (6.3%) | 79 (3.8%) | |
| Ethnicity | ||||
| Non-Hispanic | 12,807 (96.7%) | 10,769 (96.6%) | 2,038 (97.3%) | 0.08 |
| Hispanic | 437 (3.3%) | 381 (3.4%) | 56 (2.7%) | |
| Income (census-level) | ||||
| <5% below FPL | 3,805 (28.7%) | 3,240 (29.1%) | 565 (27.0%) | 0.40 |
| 5% to <10% below FPL | 3,799 (28.7%) | 3,181 (28,5%) | 618 (29.5%) | |
| 10% to <20% below FPL | 3,194 (24.1%) | 2,685 (24.1%) | 509 (24.3%) | |
| 20% to 100% below FPL | 1,439 (10.9%) | 1,204 (10.8%) | 235 (11.2%) | |
| Unknown | 1,007 (7.6%) | 840 (7.5%) | 167 (8.0%) | |
| Education * | ||||
| <25% with <12 years of education | 11,819 (89.2%) | 9,941 (89.2%) | 1,878 (89.7%) | 0.47 |
| ≥25% with <12 years of education | 1,425 (10.8%) | 1,209 (10.8%) | 216 (10.3%) | |
| Marital Status | ||||
| Married | 7,228 (54.6%) | 6,242 (56.0%) | 986 (47.1%) | <0.0001 |
| Non-Married/Other | 5,310 (40.1%) | 4,306 (38.6%) | 1,004 (48.0%) | |
| Unknown | 706 (5.3%) | 602 (5.4%) | 104 (5.0%) | |
| SEER Registry Region | ||||
| Northeast | 3,037 (22.9%) | 2,502 (22.4) | 545 (25.6) | 0.0005 |
| Midwest | 3,029 (22.9%) | 2,532 (22.7%) | 497 (23.7%) | |
| South | 1,938 (14.6%) | 1,624 (14.6%) | 314 (15.0%) | |
| West | 5,240 (39.6%) | 4,492 (40.3%) | 748 (35.7%) | |
| Urbanicity | ||||
| Metro | 11,054 (83.5%) | 9,296 (83.4%) | 1,758 (84.0%) | 0.80 |
| Urban | 1,899 (14.3%) | 1,607 (14.4%) | 292 (13.9%) | |
| Rural | 291 (2.2%) | 247 (2.2%) | 44 (2.1%) | |
| Charlson Comorbidity Score | ||||
| 0 | 6,232 (47.1%) | 5,521 (49.5%) | 711 (34.0%) | <0.0001 |
| 1 | 3,359 (25.4%) | 2,821 (25.3%) | 538 (25.7%) | |
| 2+ | 3,653 (27.6%) | 2,808 (25.2%) | 845 (40.4%) | |
| DLBCL Stage | ||||
| I | 3,853 (29.1%) | 3,257 (29.2%) | 596 (28.5%) | 0.20 |
| II | 2,158 (16.3%) | 1,842 (16.5%) | 316 (15.1%) | |
| III | 1,864 (14.1%) | 1,572 (14.1%) | 292 (13.9%) | |
| IV | 4,505 (34.0%) | 3,748 (33.6%) | 757 (36.2%) | |
| Unstaged | 864 (6.5%) | 731 (6.6%) | 133 (6.4%) | |
| Extranodal Disease | ||||
| Yes | 5,093 (38.5%) | 4,276 (38.4%) | 817 (39.0%) | 0.57 |
| No | 8,151 (61.5%) | 6,874 (61.7%) | 1,277 (61.0%) | |
| Year of Diagnosis | ||||
| 2001–2003 | 2,812 (21.2%) | 2,439 (21.9%) | 373 (17.8%) | <0.0001 |
| 2004–2007 | 4,229 (31.9%) | 3,642 (32.7%) | 587 (28.0%) | |
| 2008–2011 | 4,024 (30.4%) | 3,359 (30.1%) | 665 (31.8%) | |
| 2012–2013 | 2,179 (16.5%) | 1,710 (15.3%) | 469 (22.4%) | |
| B Symptoms *** | ||||
| Absent | 4,078 (30.8%) | 3,360 (30.1%) | 718 (34.3%) | <0.0001 |
| Present | 1,590 (12.0%) | 1,313 (11.8%) | 277 (13.2%) | |
| Unknown | 4,283 (14.1%) | 3,696 (33.2%) | 587 (28.0%) | |
| NA | 3,293 (24.9%) | 2,781 (24.9%) | 512 (24.5%) |
*
Nonwhite race includes 49 patients with unknown race
**
Education based on census-level; if census tract missing, based on zip code
***
Diagnoses prior to 2004 coded as unknown
FPL: Federal Poverty Level