Table 4.

Multivariable logistic regression with outcome disease status

	Mild-Moderate diseaseaOR, [95% CI]	P value	Severe diseaseaOR, [95% CI]	P value
Variant
Delta	1 [Reference]		1 [Reference]
Omicron	0.36 (0.23, 0.56)	<0.0001	0.57 (0.32, 1.01)	0.0687
Race
Black	1 [Reference]		1 [Reference]
White	1.62 (1.01, 2.61)	0.0565	0.91 (0.47, 1.77)	0.7959
Other	1.57 (0.56 4.44)	0.345	2.08 (0.54, 8)	0.2677
Unknown	2.39 (0.26, 21.76)	0.4451	2.23 (0.22, 22.87)	0.5456
Comorbidities
Diabetes mellitus	1.06 (0.64, 1.75)	0.815	1.51 (0.78, 2.94)	0.1991
Hypertension	2.98 (1.92, 4.66)	<0.0001	1.32 (0.72, 2.44)	0.3933
Coronary artery disease	1.1 (0.6, 2.01)	0.7623	0.54 (0.23, 1.26)	0.1159
Kidney disease	2.12 (1.2, 3.78)	0.0101	4.26 (1.97, 9.21)	<0.0001
Cancer	1.55 (0.66, 3.6)	0.3538	6.9 (2.53, 18.73)	<0.0001
Respiratory disease	1.37 (0.84, 2.25)	0.2331	5.78 (3.16, 10.59)	<0.0001
Liver disease	0.61 (0.27, 1.38)	0.2656	3.91 (1.65, 9.3)	0.0022
Vaccination status
None	1 [Reference]		1 [Reference]
One dose	1 (0.23, 4.44)	0.9963	0 (N/A, N/A)	N/A
Two doses	1.24 (0.76, 1.99)	0.3716	0.45 (0.23, 0.88)	0.0102
Three doses	3.2 (1.43, 7.17)	0.0068	0.54 (0.18, 1.62)	0.2801
BMI
Underweight	0.74 (0.23, 2.39)	0.6715	0.12 (0.01, 1.45)	0.0035
Overweight	0.62 (0.34, 1.15)	0.1298	0.89 (0.41, 1.92)	0.7486
Obesity	1.02 (0.61, 1.7)	0.9553	0.74 (0.37, 1.48)	0.3939