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. 2023 Nov 3;10:1279907. doi: 10.3389/fsurg.2023.1279907

Table 1.

Components of modified enhanced recovery after surgery (ERAS) program.

Preoperative
 Education and counseling: verbal and written information on postoperative expectationsa
 Preoperative optimization (e.g., address smoking, alcohol use, anemia, and diabetes)
 Antimicrobial prophylaxis and skin preparation consistent with SCIP guidelines
 Pre-treatment pain control and nausea (acetaminophen, gabapentin, scopolamine)
 Regional anesthesia for open cases (transversus abdominis plane block or epidural)
 Bowel preparation with magnesium citrate or GoLYTELY at 4 pm 1 day prior to surgeryb
 Clear liquids 2–4 h prior to surgery
Intraoperative
 Short-acting anesthetic agents allowing for rapid awakening (e.g., propofol and sevoflurane)
 Opioid-sparing anesthesia with limited use of long-acting opioids
 Maintain tidal volume 5–7 ml/kg (usually <500 ml) and PEEP at 4–6 cm H2O
 Multimodal antiemetics (ondansetron, metoclopramide, scopolamine)
 Maintain intraoperative temperature above 36°C
 Perioperative fluid management: maintain euvolemia
Postoperative
 Multimodal approach to postoperative nausea and vomiting with >2 antiemetics
 VTE prophylaxis: with extended prophylaxis for laparotomy for pelvic malignancy
 Termination of IV fluids within 24 h after surgery
 Regular diet within the first 24 h of surgery
 Multi-agent bowel regimen of docusate oral or suppository and polyethylene glycol 3350
 Postoperative glucose control <180
 Multimodal analgesiac
 Urinary catheter removed within 24 h of surgery
 Early mobilization within 24 h of surgery
 Postoperative day 0 discharge minimally invasive surveryd
 Postoperative day 1 discharge open surgeryd
 Discharge regimen: tramadol × 3 days, ibuprofen × 10 days, docusate × 30 daysd
Simplified discharge criteria
 Stable vital signs
 Appropriate and stable postoperative hemoglobin or hematocrit
 Adequate urine output with normal or stable kidney function
 Ability to tolerate a solid diet without vomiting, abdominal distension, or pain
 Ability to ambulate or move sufficiently enough to manage at current home environment
 Ability to tolerate pain with a multimodal pain regimen
 Voiding spontaneously unless a Foley catheter is clinically indicated
 No social barrier for postoperative recovery after discharge

SCIP, Surgical Care Improvement Project; PEEP, positive end-expiratory pressure; VTE, venous thromboembolism.

a

Postoperative expectations include information on the procedure, pain, and length of stay.

b

GoLYTELY [polyethylene glycol 3350 227.1 g, sodium sulfate (anhydrous) 21.5 g, sodium bicarbonate 6.36 g, sodium chloride 5.53 g, potassium chloride 2.82 g]—patients were instructed to drink a total of up to 1 gal at a rate of 240 ml (8 oz.) every 10 min until 1 gal is consumed or the rectal effluent is clear. Magnesium citrate—patients were instructed to drink one bottle with four glasses of water at 4 pm on 1 day prior to surgery. Patients who underwent laparoscopic surgery at our department did not have bowel preparation.

c

Including acetaminophen, ketorolac or ibuprofen, lidocaine patch, gabapentin, abdominal binder, and tramadol.

d

If no contraindication.