Table 2.

Results of univariable analysis and final model of multivariable analysis using Cox proportional hazard analysis of all-cause death

	Univariable		Multivariable
	HR (95% CI)	p	HR (95% CI)	p
Age	1.033 (1.026, 1.041)	< 0.001	1.021 (1.013, 1.030)	< 0.001
Female (reference: male)	0.972 (0.815, 1.160)	0.756
NYHA class (reference: class IV)	0.410 (0.345, 0.487)	< 0.001	0.551 (0.458, 0.663)	< 0.001
Heart rate	1.008 (1.004, 1.012)	< 0.001
LVEF	0.995 (0.990, 1.001)	0.089
Systolic BP	0.994 (0.990, 0.998)	0.002
Diastolic BP	0.985 (0.979, 0.991)	< 0.001	0.992 (0.985, 0.998)	0.011
WBC	1.072 (1.051, 1.093)	< 0.001
CRP	1.012 (1.010, 1.014)	< 0.001	1.008 (1.005, 1.010)	< 0.001
ALT	1.003 (1.002, 1.004)	< 0.001
AST	1.005 (1.004, 1.005)	< 0.001	1.002 (1.001, 1.004)	< 0.001
Uric acid	1.002 (1.001, 1.002)	< 0.001	1.001 (1.000, 1.001)	0.002
eGFR	0.973 (0.968, 0.978)	< 0.001
Sodium	0.937 (0.918, 0.955)	< 0.001
Potassium	1.143 (0.986, 1.325)	0.077
Chlorine	0.930 (0.913, 0.947)	< 0.001	0.972 (0.954, 0.991)	0.003
Lg BNP	5.754 (4.185, 7.911)	< 0.001	3.008 (2.130, 4.250)	< 0.001
GNRI	0.948 (0.937, 0.959)	< 0.001	0.967 (0.954, 0.980)	< 0.001
Lg ALI	0.139 (0.109, 0.178)	< 0.001	0.407 (0.296, 0.560)	< 0.001

① Corrected for age, NYHA class, heart rate, systolic BP, diastolic BP, ALT, AST, creatinine, uric acid, eGFR, sodium, chloride, lg BNP

② HR hazard ratio, CI confidence interval, NYHA New York Heart Association, LVEF left ventricular ejection fraction, BP blood pressure, WBC white blood cells, CRP C-reactive protein, ALT alanine aminotransferase, AST aspartate aminotransferase, eGFR estimated glomerular filtration rate, BNP brain natriuretic peptide, GNRI geriatric nutritional risk index, ALI advanced lung cancer inflammation index