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. Author manuscript; available in PMC: 2024 Apr 1.
Published in final edited form as: Nat Genet. 2023 Mar 13;55(4):595–606. doi: 10.1038/s41588-023-01298-x

Extended Data Fig. 5 |. BRCA1+/mut tissues harbor increased numbers of KRT19 + cells that co-express KRT23.

Extended Data Fig. 5 |

a) Representative immunofluorescence staining for KRT23 (red) and KRT19 (green) in human mammary tissues from NonCarrier (n = 6) and BRCA1+/mut (n = 6) individuals. Yellow staining indicates epithelial cells that are KRT19/KRT23 double-positive. Scale bar = 50 μm. b) Bar graph depicting percentages of KRT19/KRT23 double-positive cells in lobular and ductal regions of epithelial tissues and whole tissue (lobular + ductal regions) of human mammary tissues from NonCarrier (n = 6) and BRCA1+/mut (n = 6) individuals. Values are represented as mean ± SD from counts of at least 5 different random fields per tissue. P values were determined by unpaired two-tailed t-tests.