Figure 5.
Tumor microenvironment analyses between the high and low ICD subtypes. (a) Violin plots of immune and tumor purity scores. (b) Relative proportion of immune infiltration in each CRC sample obtained from TCGA. (c) Immune cell infiltration differences between the high and low ICD subtypes. DE of (d) multiple HLA genes and (e) immune checkpoint genes between the high and low ICD subtypes. *p < 0.05, **p < 0.01, ***p < 0.001, and ****p < 0.0001. CD: cluster of differentiation; DE: differential expression; ICD: immunogenic cell death; NK: natural killer.